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HA280

The HA280 is an innovative medical device with a loading capacity of 280±5 ml and volume of 155±3 ml, designed to remove immune substances and inflammatory mediators, and offer various clinical benefits. Made of high-quality materials such as Styrene Divinylbenzene Copolymers and Polycarbonate, this device is sterilized through irradiation and packaged in a sturdy unit measuring 185mm (L) x 90mm (W) x 96mm (H) and weighing 0.7 kg.

The HA280 is suitable for many clinical indications, including autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus, dermatosis, psoriasis, and severe acne.

Not only does the HA280 offer clinical benefits, but patients have also reported improved clinical outcomes. Those suffering from dermatosis, psoriasis, and severe acne have experienced reduced inflammation and pain levels, as well as improved skin appearance and texture. Patients with autoimmune diseases have reported a decrease in disease activity and symptoms.

HA280 Technical Properties

  • Loading Capacity: 280±5 ml
  • Volume: 155±3 ml
  • Absorbent Material: Styrene Divinylbenzene Copolymers
  • Housing Material: Polycarbonate
  • Sterilization Method: Irradiation Sterilization
  • Unit Package: 185mm(l) x 90mm(w) x 96mm(h), 0.7 kg
  • Operating Temperature: -40°C to 70°C
  • Humidity Range: 10% to 90% RH
  • Pressure Range: 0.5 to 5 bar

In addition to the aforementioned technical properties, it is important to consider the operating conditions under which the device can perform optimally. The temperature range in which the device can function effectively extends from -40°C to 70°C. This wide range allows for the device to be used in various environments, including extreme temperatures. Furthermore, the humidity range for optimal performance is between 10% to 90% relative humidity (RH). This ensures that the device can withstand different levels of moisture without compromising its functionality. Additionally, the device has been designed to withstand a pressure range of 0.5 to 5 bar. This means that it can effectively operate under different pressure conditions, making it suitable for a wide range of applications. Whether it is used in a low-pressure environment or a high-pressure setting, the device can maintain its performance and reliability. The unit package dimensions of the device are 185mm in length, 90mm in width, and 96mm in height. It weighs approximately 0.7 kg, making it compact and lightweight. This makes it easy to transport and store, without adding unnecessary bulk or weight. Overall, the technical properties of this device, combined with its ability to operate under various conditions and its compact design, make it a versatile and reliable option for a wide range of applications. Whether it is used in medical settings, research laboratories, or industrial environments, this device offers consistent and efficient performance.

Clinical Benefits

The HA280 offers a range of clinical benefits, including the ability to remove immune substances and inflammatory mediators. By effectively eliminating factors such as IL-1, IL-6, TNF-α, IgA, and more, it helps to alleviate symptoms and promote healing.

One of the key clinical benefits of the HA280 is its ability to remove immune substances. Immune substances, such as cytokines and antibodies, play a crucial role in the body’s immune response. However, in certain conditions, an overactive immune response can lead to chronic inflammation and tissue damage. The HA280’s ability to remove immune substances helps to regulate the immune system, reducing inflammation and preventing further damage. In addition to immune substances, the HA280 also targets inflammatory mediators. Inflammatory mediators are molecules that are released during the inflammatory response and contribute to the symptoms of inflammation, such as pain, redness, and swelling. By removing these mediators, the HA280 helps to reduce inflammation and alleviate associated symptoms. One specific inflammatory mediator that the HA280 targets is interleukin-1 (IL-1). IL-1 is a pro-inflammatory cytokine that plays a role in various inflammatory conditions, including rheumatoid arthritis and inflammatory bowel disease. By removing IL-1, the HA280 helps to reduce inflammation and improve symptoms in these conditions. Another inflammatory cytokine that the HA280 targets is interleukin-6 (IL-6). IL-6 is involved in the regulation of the immune response and plays a role in various inflammatory diseases, such as rheumatoid arthritis and psoriasis. By removing IL-6, the HA280 helps to reduce inflammation and alleviate symptoms in these conditions. Tumor necrosis factor-alpha (TNF-α) is another inflammatory mediator that the HA280 can effectively eliminate. TNF-α is a cytokine that plays a key role in the inflammatory response and is involved in various autoimmune diseases, including rheumatoid arthritis and Crohn’s disease. By removing TNF-α, the HA280 helps to reduce inflammation and improve symptoms in these conditions. Furthermore, the HA280 can also remove immunoglobulin A (IgA), which is an antibody that plays a role in the mucosal immune response. Elevated levels of IgA have been associated with certain autoimmune diseases, such as systemic lupus erythematosus and IgA nephropathy. By removing IgA, the HA280 helps to regulate the immune response and reduce inflammation in these conditions. Overall, the HA280 offers a range of clinical benefits by effectively removing immune substances and inflammatory mediators. Its ability to target specific cytokines and antibodies helps to alleviate symptoms and promote healing in various inflammatory and autoimmune conditions.

Clinical Indications

The HA280 is indicated for the treatment of various dermatological conditions, autoimmune diseases, and vasculitis. It has shown positive results in the following conditions:

Dermatosis

HA280 can be used to treat dermatosis, including conditions such as psoriasis, pemphigus, chloasma, severe acne, severe drug rash, and vasculitis. Dermatosis refers to a range of skin disorders characterized by inflammation, itching, and discomfort. Psoriasis, for example, is a chronic autoimmune condition that causes red, scaly patches on the skin. HA280’s efficacy in treating dermatosis is attributed to its ability to regulate immune response, reduce inflammation, and promote skin healing.

Vasculitis

The HA280 has been found to be effective in the treatment of various types of vasculitis, including allergic purpura (AP), ANCA-related vasculitis, urticarial vasculitis, polyarteritis nodosa, allergic vasculitis, Kawasaki disease, and more. Vasculitis is a group of disorders characterized by inflammation of blood vessels, which can lead to damage and dysfunction of organs and tissues. HA280’s immunosuppressive properties help to alleviate the inflammation associated with vasculitis, reducing symptoms and improving overall patient well-being.

Autoimmune Diseases

HA280 has shown promising results in the treatment of autoimmune diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Behcet’s disease, multiple myositis, rachitis, systemic scleroderma, and sicca syndrome. Autoimmune diseases occur when the body’s immune system mistakenly attacks its own tissues, leading to chronic inflammation and tissue damage. HA280’s ability to modulate immune response and suppress the abnormal immune activity makes it an effective therapeutic option for managing autoimmune diseases. By reducing inflammation and preventing further tissue damage, HA280 helps to alleviate symptoms and improve quality of life for patients.

With its advanced technical properties and proven clinical benefits, the HA280 is a reliable and effective option for healthcare professionals seeking to improve patient outcomes in the treatment of various dermatological conditions, autoimmune diseases, and vasculitis. Its versatility in addressing different disease states and its ability to target the underlying immune dysregulation make it a valuable tool in the management of these complex conditions. As further research and clinical trials continue to explore the potential applications of HA280, its role in the field of dermatology, autoimmune diseases, and vasculitis treatment is expected to expand, providing new hope and improved therapeutic options for patients worldwide.

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